Nathan P Wiederhold Selected Research

Invasive Pulmonary Aspergillosis

5/2015	Efficacy of the investigational echinocandin ASP9726 in a guinea pig model of invasive pulmonary aspergillosis.
8/2013	Prolyl endopeptidase activity in bronchoalveolar lavage fluid: a novel diagnostic biomarker in a guinea pig model of invasive pulmonary aspergillosis.
2/2013	Interlaboratory and interstudy reproducibility of a novel lateral-flow device and influence of antifungal therapy on detection of invasive pulmonary aspergillosis.
8/2012	Dry powder insufflation of crystalline and amorphous voriconazole formulations produced by thin film freezing to mice.
4/2012	Prophylactic efficacy of single dose pulmonary administration of amphotericin B inhalation powder in a guinea pig model of invasive pulmonary aspergillosis.
3/2012	Detection and measurement of fungal burden in a guinea pig model of invasive pulmonary aspergillosis by novel quantitative nested real-time PCR compared with galactomannan and (1,3)-β-D-glucan detection.
12/2009	Comparison of lateral flow technology and galactomannan and (1->3)-beta-D-glucan assays for detection of invasive pulmonary aspergillosis.
6/2009	Inhaled voriconazole for prevention of invasive pulmonary aspergillosis.
3/2008	Assessment of serum (1->3)-beta-D-glucan concentration as a measure of disease burden in a murine model of invasive pulmonary aspergillosis.
7/2007	Aerosolized nanostructured itraconazole as prophylaxis against invasive pulmonary aspergillosis.

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Nathan P Wiederhold Research Topics

Disease

35	Infections 06/2021 - 01/2005
17	Invasive Fungal Infections 02/2021 - 12/2007
16	Aspergillosis 01/2022 - 12/2003
13	Body Weight (Weight, Body) 01/2020 - 02/2006
13	Invasive Pulmonary Aspergillosis 05/2015 - 10/2004
12	Invasive Candidiasis 08/2022 - 01/2008
11	Mycoses (Diseases, Fungus) 12/2021 - 08/2003
8	Mucormycosis 04/2021 - 07/2013
4	Fusariosis 07/2021 - 01/2006
3	Candidiasis (Moniliasis) 08/2022 - 01/2012
3	Cryptococcal Meningitis 11/2018 - 01/2016
3	Coccidioidomycosis 01/2018 - 12/2015
3	Cryptococcosis 12/2016 - 02/2013
2	Fever (Fevers) 06/2021 - 04/2017
2	Cystic Fibrosis (Mucoviscidosis) 06/2021 - 03/2017
2	Candidemia 07/2019 - 09/2013
2	Chronic Granulomatous Disease 06/2019 - 01/2017
2	Drug-Related Side Effects and Adverse Reactions 03/2018 - 01/2018
2	Meningoencephalitis 02/2013 - 06/2012
2	Pulmonary Edema 03/2010 - 09/2009
2	Neoplasms (Cancer) 12/2005 - 01/2005
1	Breakthrough Infections 06/2021
1	Coinfection 06/2021
1	Surgical Wound 06/2021
1	Legg-Calve-Perthes Disease (Perthes Disease) 06/2021
1	Wounds and Injuries (Trauma) 06/2021
1	Pain (Aches) 06/2021
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2021
1	Leukemia 01/2021
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2021
1	scedosporiosis 01/2020
1	Bacterial Infections (Bacterial Infection) 12/2019
1	Granuloma 06/2019
1	Weight Loss (Weight Reduction) 03/2019
1	Diarrhea 03/2019
1	Colitis 03/2019
1	Ileitis 03/2019
1	Pythiosis 03/2019
1	Alopecia (Baldness) 01/2019

Drug/Important Bio-Agent (IBA)

18	EchinocandinsIBA 10/2019 - 12/2007
14	AzolesIBA 01/2022 - 06/2007
11	posaconazole FDA Link 06/2021 - 03/2010
11	Fluconazole (Zonal)FDA LinkGeneric 01/2021 - 02/2013
10	Caspofungin (Cancidas)FDA Link 11/2019 - 08/2003
9	Voriconazole (Vfend)FDA LinkGeneric 01/2019 - 06/2009
7	Antifungal AgentsIBA 01/2018 - 03/2008
7	Pharmaceutical PreparationsIBA 01/2017 - 04/2005
7	Amphotericin B (Amphotericin)FDA LinkGeneric 10/2015 - 02/2006
6	isavuconazoleIBA 06/2021 - 01/2016
5	Itraconazole (Sporanox)FDA LinkGeneric 01/2019 - 04/2006
5	Micafungin (FK463)FDA Link 01/2017 - 08/2003
4	olorofimIBA 07/2021 - 11/2016
4	VT-1161IBA 01/2019 - 12/2015
3	ibrexafungerpIBA 08/2022 - 01/2018
3	Investigational DrugsIBA 08/2022 - 12/2015
3	liposomal amphotericin B FDA Link 04/2021 - 07/2013
3	EnzymesIBA 01/2020 - 01/2017
3	VT-1598IBA 01/2019 - 01/2018
3	galactomannanIBA 04/2016 - 12/2009
3	polyglucosanIBA 04/2016 - 03/2008
2	CytokinesIBA 04/2021 - 06/2007
2	Pentamidine (NebuPent)FDA LinkGeneric 02/2021 - 01/2006
2	T-2307IBA 02/2021 - 02/2015
2	ProdrugsIBA 01/2020 - 01/2020
2	1-aminobenzotriazoleIBA 01/2020 - 01/2020
2	TriazolesIBA 01/2020 - 01/2019
2	APX001AIBA 01/2020 - 01/2015
2	RezafunginIBA 10/2019 - 11/2018
2	Anti-Bacterial Agents (Antibiotics)IBA 03/2019 - 06/2015
2	Ergosterol (Lumisterol)IBA 01/2019 - 03/2018
2	VT-1129IBA 11/2018 - 01/2018
2	glucan synthaseIBA 01/2018 - 08/2003
2	Indicators and Reagents (Reagents)IBA 04/2016 - 01/2005
2	Biomarkers (Surrogate Marker)IBA 08/2013 - 03/2008
2	Anidulafungin FDA Link 05/2007 - 08/2003
2	Adrenal Cortex Hormones (Corticosteroids)IBA 02/2006 - 12/2003
2	GliotoxinIBA 12/2005 - 01/2005
1	ChemokinesIBA 04/2021
1	venetoclaxIBA 01/2021
1	DNA ProbesIBA 11/2020
1	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 01/2020
1	mannoproteinsIBA 01/2020
1	Volatile Oils (Essential Oils)IBA 12/2019
1	NADPH Oxidases (NAD(P)H oxidase)IBA 06/2019
1	Formaldehyde (Formol)FDA Link 03/2019
1	Coloring Agents (Dyes)IBA 03/2019
1	ImmunosorbentsIBA 03/2019
1	Methenamine (Hexamine)IBA 03/2019
1	ParaffinIBA 03/2019
1	ebericolIBA 01/2019
1	HMGB1 Protein (HMG1)IBA 01/2019
1	SterolsIBA 01/2019
1	ebselenIBA 10/2018

Therapy/Procedure

29	Therapeutics 01/2022 - 12/2003
3	Salvage Therapy 01/2019 - 03/2010
2	Lung Transplantation 06/2021 - 03/2017
1	Hip Replacement Arthroplasty (Total Hip Replacement) 06/2021
1	Remission Induction 01/2021
1	Drug Therapy (Chemotherapy) 01/2021
1	Intraperitoneal Injections 11/2019